BDBM50553485 CHEMBL4790952

SMILES CN1CC[C@H]([C@@H]1CO)c1c(OP(O)(O)=O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl

InChI Key InChIKey=LXRJNNLNUWGVCX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50553485   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553485(CHEMBL4790952)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9/cyclin-T1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553485(CHEMBL4790952)
Affinity DataIC50: 63nMAssay Description:Inhibition of human CDK4/cyclin D1 expressed in baculovirus infected Sf9 cells using GST-retinoblastoma (776 to 928 residues) as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553485(CHEMBL4790952)
Affinity DataIC50: 79nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553485(CHEMBL4790952)
Affinity DataIC50: 224nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553485(CHEMBL4790952)
Affinity DataIC50: 396nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed