BDBM50553526 CHEMBL4746217

SMILES Cc1cc(nc(n1)N1CCC(COc2ccccc2C(F)(F)F)C1)C(O)=O

InChI Key InChIKey=YNIAPSNMAZHUHD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50553526   

TargetRetinol-binding protein 4(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50553526(CHEMBL4746217)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]-all-trans-retinol from MBP-tagged RBP4 (unknown origin) expressed in Escherichia coli assessed as reduction in untagged Eu-label...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetTransthyretin(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50553526(CHEMBL4746217)
Affinity DataIC50: 2.85E+3nMAssay Description:Displacement of FITC-diclofenac from human plasma derived TTR measured after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50553526(CHEMBL4746217)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50553526(CHEMBL4746217)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRetinol-binding protein 4(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50553526(CHEMBL4746217)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]-all-trans-retinol from biotinylated human urine derived RBP4 measured after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed