BDBM50553792 CHEMBL4797488

SMILES ONC(=O)c1ccc(CN2C(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c3ccccc23)cc1

InChI Key InChIKey=PCUHSWONNREECS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50553792   

TargetHistone deacetylase 6(Human)
Hanoi University of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50553792(CHEMBL4797488)
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Hanoi University of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50553792(CHEMBL4797488)
Affinity DataIC50: 195nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using fluoroscence-labeled acetylated peptide as substrate by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Hanoi University of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50553792(CHEMBL4797488)
Affinity DataIC50: 205nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed