BDBM50554155 CHEMBL4793341

SMILES FC(F)(F)Oc1ccc(CNC2CCN(Cc3ccccc3)C2)cc1

InChI Key InChIKey=RLLGGQDQUFVCQL-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554155   

TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50554155(CHEMBL4793341)
Affinity DataKi:  23nMAssay Description:Mixed type inhibition of human AChE assessed as dissociation constant using varying level acetylthiocholine iodide as substrate by Dixon plot analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50554155(CHEMBL4793341)
Affinity DataIC50: 58nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50554155(CHEMBL4793341)
Affinity DataIC50: 82nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50554155(CHEMBL4793341)
Affinity DataIC50: 115nMAssay Description:Inhibition of human BACE-1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed