BDBM50554439 CHEMBL4752642

SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(CNc3c(NCCNC(=O)C=C)c(=O)c3=O)cc2)ncc1Cl

InChI Key InChIKey=UTSSJQUIRGMHJS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554439   

TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554439(CHEMBL4752642)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554439(CHEMBL4752642)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50554439(CHEMBL4752642)
Affinity DataKi:  0.230nMAssay Description:Covalent inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed