BDBM50554836 CHEMBL4753546

SMILES CCCC(C)n1c2[nH]c3cc(ccc3c2c(=O)c2cc(OC)c(cc12)N1CCN(C)CC1)C#N

InChI Key InChIKey=BVUHUOSWVJZOAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554836   

TargetALK tyrosine kinase receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50554836(CHEMBL4753546)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of N-terminal GST tagged wild-type human ALK cytoplasmic domain (1058-1620 amino acids) expressed Sf9 cells pre-incubated for 30 mins befo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed