BDBM50555369 CHEMBL4740960

SMILES Cc1cc(NC2CCc3cc(F)ccc3C2)n2nc(nc2n1)C(C)(F)F

InChI Key InChIKey=CVWRIJKCARXPJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50555369   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50555369(CHEMBL4740960)
Affinity DataIC50: 700nMAssay Description:Inhibition of human ERG by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50555369(CHEMBL4740960)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged human DHODH expressed in Escherichia coli BL21 using L-DHO as substrate and CoQ as co-substrate by DCIP dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed