BDBM50555463 CHEMBL4799530

SMILES COc1ncc(cn1)-c1nc(N2CCOCC2)c2ncn(CCCCCCC(=O)NO)c2n1

InChI Key InChIKey=BFQLNFXKRXENAT-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50555463   

LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 331nMAssay Description:Inhibition of human PI3Kdelta incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
A*Star

Curated by ChEMBL
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate measured after 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 376nMAssay Description:Inhibition of human full-length recombinant p110alpha/p85alpha co-expressed in baculovirus expression system using PIP2:PS lipid as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 136nMAssay Description:Inhibition of human PI3Kalpha incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human PI3Kbeta incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 692nMAssay Description:Inhibition of human PI3Kgamma incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
A*Star

Curated by ChEMBL
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of human mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3K2alpha incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3K2beta (unknown origin) incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIK3C3 incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
A*Star

Curated by ChEMBL
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI4kbeta incubated for 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
LigandPNGBDBM50555463(CHEMBL4799530)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed