BDBM50555467 CHEMBL4758971

SMILES Nc1ncc(cn1)-c1nc(nc2n(CCCCCC(=O)NO)cnc12)N1CCOCC1

InChI Key InChIKey=PANIUKDSNUOBOH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50555467   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
A*Star

Curated by ChEMBL

LigandBDBM50555467(CHEMBL4758971)Copy SMILESCopy InChI

Affinity DataIC50: 9.20nMAssay Description:Inhibition of human full-length recombinant p110alpha/p85alpha co-expressed in baculovirus expression system using PIP2:PS lipid as substrate incubat...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/26/2022
Entry Details Article
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TargetHistone deacetylase 1(Human)
A*Star

Curated by ChEMBL

LigandBDBM50555467(CHEMBL4758971)Copy SMILESCopy InChI

Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate measured after 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/26/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL