BDBM50555486 CHEMBL4764799

SMILES Nc1ncc(cn1)-c1nc(N2CCC(CO)CC2)c2ncn(CCCCCCC(=O)NO)c2n1

InChI Key InChIKey=RKDDEGABLQYMCZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50555486   

TargetHistone deacetylase 1(Human)
A*Star

Curated by ChEMBL

LigandBDBM50555486(CHEMBL4764799)Copy SMILESCopy InChI

Affinity DataIC50: 0.990nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate measured after 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/26/2022
Entry Details Article
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
A*Star

Curated by ChEMBL

LigandBDBM50555486(CHEMBL4764799)Copy SMILESCopy InChI

Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human full-length recombinant p110alpha/p85alpha co-expressed in baculovirus expression system using PIP2:PS lipid as substrate incubat...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/26/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL