BDBM50555591 CHEMBL4754820

SMILES COC(=O)c1ccc(Nc2ccc3N(CCCc3c2)S(=O)(=O)N(C)Cc2ccc(cc2)C(C)(C)C)cc1

InChI Key InChIKey=QOTBNWCJURNORO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50555591   

TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50555591(CHEMBL4754820)
Affinity DataIC50: 637nMAssay Description:Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of europium-labeled co-activator SRC1 recruitment incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed