BDBM50555594 CHEMBL4745031

SMILES CN(Cc1ccccc1)S(=O)(=O)N1CCCc2cc(ccc12)N1CCN(CC1)C(C)=O

InChI Key InChIKey=HGIVSBUXSHCSJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50555594   

TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555594BDBM50555594(CHEMBL4745031)
Affinity DataIC50: 218nMAssay Description:Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of europium-labeled SRC-1 recruitment incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50555594BDBM50555594(CHEMBL4745031)
Affinity DataIC50: 4.93E+3nMAssay Description:Inverse agonist activity at RORgammat in mouse CD4+ T cells assessed as inhibition of differentiation into Th17 cells by measuring IL-17 production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed