BDBM50555923 CHEMBL4748100

SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(cc(C)c4=O)-c4ccccc4)cc3)ccnc2cc1OCCCCCCC(=O)NO

InChI Key InChIKey=SIAHWSSTPPXGSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50555923   

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50555923(CHEMBL4748100)
Affinity DataIC50: 20nMAssay Description:Inhibition of c-MET(unknown origin) using FAM labelled peptide substrate preincubated for 10 mins followed by substrate addition and measured by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50555923(CHEMBL4748100)
Affinity DataIC50: 34nMAssay Description:Inhibition of human C-terminal Flag tagged HDAC1 (1 to 482 residues) expressed in SF9 cells using Ac-peptide substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed