BDBM50556084 CHEMBL4791447

SMILES Cc1c(sc2nc3ccccc3n12)C(=O)\C=C\NCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=FRGAZFAUGGQURK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50556084   

TargetCarbonic anhydrase 2(Human)
Jouf University

Curated by ChEMBL
LigandPNGBDBM50556084(CHEMBL4791447)
Affinity DataKi:  12nMAssay Description:Inhibition of human CA2 preincubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Jouf University

Curated by ChEMBL
LigandPNGBDBM50556084(CHEMBL4791447)
Affinity DataKi:  56nMAssay Description:Inhibition of human CA9 preincubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Jouf University

Curated by ChEMBL
LigandPNGBDBM50556084(CHEMBL4791447)
Affinity DataKi:  72nMAssay Description:Inhibition of human CA12 preincubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Jouf University

Curated by ChEMBL
LigandPNGBDBM50556084(CHEMBL4791447)
Affinity DataKi:  218nMAssay Description:Inhibition of human CA1 preincubated for 15 mins prior to testing by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed