BDBM50556421 CHEMBL4781649

SMILES Cc1ccc(cc1)C(=O)c1cnc(NC(=O)C2(CC2)c2ccc3OCOc3c2)s1

InChI Key InChIKey=ZNOUSIMRSVOAFX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50556421   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50556421(CHEMBL4781649)
Affinity DataEC50:  2.57E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed