BDBM50556442 CHEMBL4788444

SMILES COc1ccc(C(=O)c2sc(NC(=O)C3(CC3)c3ccc4OCOc4c3)nc2-c2ccccc2)c(OC)c1

InChI Key InChIKey=VUGOWDLTQHDEBG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50556442   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50556442(CHEMBL4788444)
Affinity DataEC50:  400nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed