BDBM50556682 CHEMBL4794655

SMILES Cc1nc(Cl)cc(Nc2c[nH]nc2-c2nc(c[nH]2)-c2ccc(CN3CCOCC3)cc2)n1

InChI Key InChIKey=JCGXVWCLMLBCHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556682   

TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556682(CHEMBL4794655)
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556682(CHEMBL4794655)
Affinity DataIC50: 23nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556682(CHEMBL4794655)
Affinity DataIC50: 145nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed