BDBM50556880 CHEMBL4796668::US11299480, Example 63

SMILES CC(C)c1ccc(CN(C(=O)[C@H]2CCN2S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c2cc(O)c(cc2F)C(O)=O)cc1

InChI Key InChIKey=SELLKXQAKJSBIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50556880   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM50556880(CHEMBL4796668 | US11299480, Example 63)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii

US Patent
LigandPNGBDBM50556880(CHEMBL4796668 | US11299480, Example 63)
Affinity DataIC50: 1.28E+3nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2022
Entry Details
Go to US Patent