BDBM50557571 CHEMBL4789884

SMILES Cc1ccc(Nc2nc(\C=C\c3ccccc3)nc3ccccc23)cc1

InChI Key InChIKey=OKHWBLRPRFHOCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557571   

TargetProstaglandin G/H synthase 1(Sheep)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50557571(CHEMBL4789884)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50557571(CHEMBL4789884)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed