BDBM50557576 CHEMBL4763348

SMILES Fc1ccc(CNc2nc(Cl)nc3cc(ccc23)-c2cccs2)cc1F

InChI Key InChIKey=IIFSHMRLQNEOMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557576   

TargetProstaglandin G/H synthase 1(Sheep)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50557576(CHEMBL4763348)
Affinity DataIC50: 142nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50557576(CHEMBL4763348)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed