BDBM50557724 CHEMBL4763003

SMILES O=C(Nc1nc2ccncc2s1)[C@@H]1C[C@H]1c1ccc(cc1)S(=O)(=O)Nc1ccccn1

InChI Key InChIKey=PXLAOJRRWUJJHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50557724   

TargetRho-associated protein kinase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557724(CHEMBL4763003)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2 (unknown origin) using KRRRLSSLRA as substrate incubated for 75 mins in presence of ATP and DTT by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed