BDBM50557725 CHEMBL4783299

SMILES O=C(Nc1ccc2cnccc2n1)[C@@H]1C[C@H]1c1ccc(cc1)S(=O)(=O)Nc1ccccn1

InChI Key InChIKey=IBDDMLHLHUWMJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50557725   

TargetRho-associated protein kinase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557725(CHEMBL4783299)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2 (unknown origin) using KRRRLSSLRA as substrate incubated for 75 mins in presence of ATP and DTT by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed