BDBM50557785 CHEMBL4758829

SMILES OC(=O)c1ccc(cc1)-n1nc(cc1-n1cc(CNc2ccc([N+]([O-])=O)c3nonc23)nn1)-c1ccco1

InChI Key InChIKey=LLTXARCQIUWLCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557785   

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557785(CHEMBL4758829)
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557785(CHEMBL4758829)
Affinity DataIC50: 900nMAssay Description:Inhibition of COX1 in human OVCAR-3 cells assessed as reduction in PGE2 level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50557785(CHEMBL4758829)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed