BDBM50557832 CHEMBL4742368

SMILES CC(C)S(=O)(=O)c1c(Cl)ccc(NC2=NC(=O)[C@H](N2)C2CCCCC2)c1O

InChI Key InChIKey=JJJRSKYLYIDEHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557832   

TargetC-X-C chemokine receptor type 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50557832(CHEMBL4742368)
Affinity DataIC50: 10nMAssay Description:Antagonist activity in CXCR2 (unknown origin) expressed in human HEK293 cells co-expressing Galpha16 assessed as reduction in calcium immobilization ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50557832(CHEMBL4742368)
Affinity DataIC50: 9.10E+3nMAssay Description:Antagonist activity in CXCR1 (unknown origin) expressed in human HEK293 cells co-expressing Galpha16 assessed as reduction in calcium immobilization ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50557832(CHEMBL4742368)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed