BDBM50557846 CHEMBL4762877::US20250346922, Compound II-11

SMILES CC(C)(Nc1ncc(cc1F)C(=O)NO)c1ccccc1

InChI Key InChIKey=UBQIKAUELOOSBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557846   

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50557846BDBM50557846(CHEMBL4762877 | US20250346922, Compound II-11)
Affinity DataIC50: 0.639nMAssay Description:The compounds disclosed herein, in particular those of Formula (II), were synthesized according to methods disclosed in WO 2021/067859, which is inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50557846BDBM50557846(CHEMBL4762877 | US20250346922, Compound II-11)
Affinity DataIC50: 0.639nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using luminescent substrate by HDAC-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed