BDBM50557899 CHEMBL4764192

SMILES OC(=O)[C@H]1CC[C@H](Cn2c(=O)n(Cc3cccc(c3C#N)C(F)(F)F)c3cccc(F)c3c2=O)CC1

InChI Key InChIKey=HPTLPJWLCDNFFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557899   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50557899(CHEMBL4764192)
Affinity DataIC50: 40nMAssay Description:Inhibition of human TNKS1 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50557899(CHEMBL4764192)
Affinity DataIC50: 316nMAssay Description:Inhibition of human TNKS2 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed