BDBM50557937 CHEMBL4754371

SMILES CN(C)c1ccc(C=CC=Cc2cc(C)[n+](CCNC(=O)CCc3cn(CCCCC4CCN(CC(=O)N5c6ccccc6NC(=O)c6ccccc56)CC4)cn3)c(C)c2)cc1

InChI Key InChIKey=BDWDGROOZISTTC-UHFFFAOYSA-O

Data  5 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50557937   

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557937(CHEMBL4754371)
Affinity DataKd:  2nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557937(CHEMBL4754371)
Affinity DataKd:  2nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557937(CHEMBL4754371)
Affinity DataKi:  0.912nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557937(CHEMBL4754371)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557937(CHEMBL4754371)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557937(CHEMBL4754371)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557937(CHEMBL4754371)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed