BDBM50557939 CHEMBL4742721

SMILES F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(C=Cc3ccc(OCC(=O)NCCCCCC(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc67)CC5)cn4)cc3)=[N+]12

InChI Key InChIKey=PHRZGNXUUFTVSE-UHFFFAOYSA-N

Data  5 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50557939   

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557939(CHEMBL4742721)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557939(CHEMBL4742721)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to human muscarinic M2 receptor expressed in CHO-K9 cells assessed as unspecific binding at Kd incubated in dark at 22 degree C for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557939(CHEMBL4742721)
Affinity DataKi:  0.417nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557939(CHEMBL4742721)
Affinity DataKi:  0.692nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557939(CHEMBL4742721)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557939(CHEMBL4742721)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO-K1 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50557939(CHEMBL4742721)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO-K9 cell membranes measured after 3 hrs by radioligand competit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed