BDBM50558007 CHEMBL4749692

SMILES [#8]-c1ccc(cc1)-[#6](\[#6]-n1cnnc1)=[#6](/c1ccc(-[#8])cc1)-c1ccc(-[#8])cc1

InChI Key InChIKey=AIRISEHPDWSAPZ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50558007   

TargetEstrogen receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558007(CHEMBL4749692)
Affinity DataEC50:  943nMAssay Description:Displacement of ES2 from recombinant human ER-alpha incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558007(CHEMBL4749692)
Affinity DataEC50:  1.08E+3nMAssay Description:Displacement of ES2 from recombinant human ER-beta incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAromatase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558007(CHEMBL4749692)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of recombinant human aromatase incubated for 30 mins using fluorometric substrate 7-methoxy-4-trifluoromethylcoumarin in presence of NADPH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed