BDBM50558254 CHEMBL4800312

SMILES O\N=C(\Cc1ccc(Br)cc1)Nc1ccc([N+]([O-])=O)c2nonc12

InChI Key InChIKey=GJNYYWZEIOAHAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558254   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Indian Institute of Technology Guwahati

Curated by ChEMBL
LigandPNGBDBM50558254(CHEMBL4800312)
Affinity DataIC50: 112nMAssay Description:Inhibition of recombinant human IDO1 assessed as N-formylkynurenine formation using L-tryptophan as substrate measured after 1 hr by UV-vis spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Indian Institute of Technology Guwahati

Curated by ChEMBL
LigandPNGBDBM50558254(CHEMBL4800312)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of recombinant human TDO assessed as N-formylkynurenine formation using L-tryptophan as substrate measured after 1 hrs by UV-vis spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed