BDBM50558301 CHEMBL4763609

SMILES O=C(CSc1nc2ccccc2c(=O)n1CCc1ccccn1)NNC(=O)c1ccccc1

InChI Key InChIKey=NHVRFKZMNQDRCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558301   

TargetProstaglandin G/H synthase 2(Sheep)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50558301(CHEMBL4763609)
Affinity DataIC50: 900nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50558301(CHEMBL4763609)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed