BDBM50558314 CHEMBL4765091

SMILES COc1ccc(\C=C\C(=O)c2ccc(O)cc2)c2ccccc12

InChI Key InChIKey=ZXCAMQJWRCMHRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50558314   

TargetCathepsin B(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50558314(CHEMBL4765091)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of cathepsin B (unknown origin) using RR-AMC as substrate preincubated for 30 mins followed by substrate addition and further incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50558314(CHEMBL4765091)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of cathepsin L (unknown origin) using Z-FR-AMC as substrate preincubated for 30 mins followed by substrate addition and further incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50558314(CHEMBL4765091)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human erythrocytes mu-calpain using Pep1 as substrate incubated for 30 mins under shaking condition in presence of CaCl2 by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed