BDBM50558375 CHEMBL4780286

SMILES OC[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=HGYWFXIFINVXSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50558375   

TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu)

Curated by ChEMBL
LigandPNGBDBM50558375(CHEMBL4780286)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EGFR (unknown origin) using Tyr 04 peptide as substrate incubated for 1 hr by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu)

Curated by ChEMBL
LigandPNGBDBM50558375(CHEMBL4780286)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human EGFR using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]ATP by radiometric HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Norwegian University of Science and Technology (Ntnu)

Curated by ChEMBL
LigandPNGBDBM50558375(CHEMBL4780286)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by IonWorks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed