BDBM50558405 CHEMBL4787816

SMILES COc1cc(CNCCN(C)C)ccc1-c1cc2c(N[C@H](CO)c3ccccc3)ncnc2[nH]1

InChI Key InChIKey=SPDGVJBWBHGXCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558405   

TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (Ntnu)

Curated by ChEMBL
LigandPNGBDBM50558405(CHEMBL4787816)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human EGFR using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]ATP by radiometric HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Norwegian University of Science and Technology (Ntnu)

Curated by ChEMBL
LigandPNGBDBM50558405(CHEMBL4787816)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by IonWorks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed