BDBM50558620 CHEMBL4789066

SMILES Oc1ccc(NS(=O)(=O)c2ccc3C(=O)c4ccccc4C(=O)c3c2)cc1

InChI Key InChIKey=CQXWZOXSWDZDPK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558620   

TargetSignal transducer and activator of transcription 3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50558620(CHEMBL4789066)
Affinity DataKd:  4.59E+3nMAssay Description:Binding affinity to STAT3 (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50558620(CHEMBL4789066)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of STAT3-dependent transcriptional activity in human HeLa cells transfected with p-Luc-TKS3 assessed as reduction in luciferase expression...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed