BDBM50558667 CHEMBL4761077

SMILES [H][C@@]12COP(O)(=O)O[C@]3([H])[C@H](O)[C@@]([H])(COP(O)(=O)O[C@]([H])([C@@H]1O)[C@@H](O2)n1cnc2c(N)ncnc12)O[C@H]3n1cnc2c(O)ncnc12

InChI Key InChIKey=PRDGKCXMHCGFJR-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50558667   

TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558667(CHEMBL4761077)
Affinity DataEC50:  1.74E+4nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558667(CHEMBL4761077)
Affinity DataEC50:  1.79E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558667(CHEMBL4761077)
Affinity DataEC50:  1.11E+5nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558667(CHEMBL4761077)
Affinity DataEC50:  2.05E+4nMAssay Description:Activation of STING in human blood assessed as induction of type I IFNs incubated for 18 to 20 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed