BDBM50559670 CHEMBL4743245

SMILES CCC([C@H]1CC[C@@H](CC1)Oc1ccnc2ccccc12)c1nc2ccc(Cl)cc2[nH]1

InChI Key InChIKey=JCOMZGDVMZZLPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50559670   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50559670(CHEMBL4743245)
Affinity DataIC50: 7nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced human HeLa cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50559670(CHEMBL4743245)
Affinity DataIC50: 36nMAssay Description:Inhibition of IDO1 in IFN-gamma/LPS induced human whole blood assessed as tryptophan/kynurenine level measured after 18 hrs by RapidFire mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50559670(CHEMBL4743245)
Affinity DataIC50: 52nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed