BDBM50559708 CHEMBL4789722

SMILES COc1ccc(cc1F)-c1nc2CCCSc2c(Nc2ccc(CC(O)=O)cc2)n1

InChI Key InChIKey=QDZKLMUDTMBEOG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559708   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559708(CHEMBL4789722)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of full length human PDE4B2 expressed in baculovirus infected Sf9 cell expression system preincubated for 10 mins followed by cAMP additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559708(CHEMBL4789722)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human full length PDE4B2 assessed as cAMP by measuring fluorescence intensity preincubated for 10 mins followed by cAMP addition furthe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559708(CHEMBL4789722)
Affinity DataIC50: 440nMAssay Description:Inhibition of full length human PDE4D2 preincubated for 10 mins followed by cAMP addition and measured after 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559708(CHEMBL4789722)
Affinity DataIC50: 440nMAssay Description:Inhibition of human full length PDE4D2 assessed as cAMP by measuring fluorescence intensity preincubated for 10 mins followed by cAMP addition furthe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed