BDBM50559710 CHEMBL4793329

SMILES COc1ccc(cc1OC)-c1ccc2nc(N)nc(N3CCN(CC3)C(=O)Nc3ccc(Cl)cc3)c2n1

InChI Key InChIKey=LCJPYDPFBGENCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50559710   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559710(CHEMBL4793329)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human U937 cell derived PDE4 preincubated for 15 mins followed by [3H]AMP and cAMP addition and measured after 20 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed