BDBM50559723 CHEMBL4746212

SMILES COc1cccc(Nc2c(ccc3c(C)cc(cc23)S(=O)(=O)c2cccc(c2)C(=O)Nc2ccc(cc2)C#CCCCNC[C@@H](O)c2ccc(O)c3[nH]c(=O)ccc23)C(N)=O)c1

InChI Key InChIKey=CESHXWXLOJIPHC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559723   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559723(CHEMBL4746212)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human PDE4B2 using cAMP as substrate preincubated for 5 mins followed by substrate addition and measured after 60 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559723(CHEMBL4746212)
Affinity DataEC50:  8nMAssay Description:Agonist activity at recombinant human beta2 adrenergic receptor expressed in CHO cells in presence of [3H](-)CGP12177More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed