BDBM50560452 CHEMBL4756259

SMILES [H][C@]12O[C@@]1(C)CC\C=C(C)\CC[C@@]1([H])[C@H](CN(C)CCCOc3no[n+]([O-])c3S(=O)(=O)c3ccccc3)C(=O)O[C@]21[H]

InChI Key InChIKey=OXMGOSMLSNXEOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560452   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560452(CHEMBL4756259)
Affinity DataIC50: 400nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50560452(CHEMBL4756259)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed