BDBM50560581 CHEMBL4792948

SMILES CC(=O)Nc1nc2ccccn2c1-c1ccc(O)cc1

InChI Key InChIKey=WTGODXTULSTYNY-UHFFFAOYSA-N

Data  4 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50560581   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560581(CHEMBL4792948)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant full length USP7 (unknown origin) using di-ubiquitin as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560581(CHEMBL4792948)
Affinity DataKd:  6.80E+5nMAssay Description:Allosteric binding affinity to USP7 catalytic domain (unknown origin) at Met328, Trp285, Gly284, Gln405 and Gly313 residues by NMR-15N-1H TROSY spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560581(CHEMBL4792948)
Affinity DataKd:  5.80E+5nMAssay Description:Allosteric binding affinity to USP7 catalytic domain (unknown origin) at Met328 residues by NMR-15N-1H TROSY spectral titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560581(CHEMBL4792948)
Affinity DataKd:  5.40E+5nMAssay Description:Binding affinity to USP7 (unknown origin) by T2 relaxation experiment based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560581(CHEMBL4792948)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of USP47 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560581(CHEMBL4792948)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of USP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560581(CHEMBL4792948)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of USP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed