BDBM50560867 CHEMBL4794980

SMILES C(Cn1c2ccccc2c2ccnc(-c3ccccn3)c12)OCc1ccccc1

InChI Key InChIKey=AOXJYEAMCDIZJR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50560867   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50560867(CHEMBL4794980)
Affinity DataKi:  7.88E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged Mcl-1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50560867(CHEMBL4794980)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged Mcl-1 (171 to 327 residues) (unknown origin) expressed in Escherich...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50560867(CHEMBL4794980)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal biotin-labeled BIM BH3 peptide (141 to 166 residues) binding to His-tagged Mcl-1 (171 to 327 residues) (unknown origin) expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed