BDBM50560909 CHEMBL4759584

SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Nc1ccc(CN)cc1

InChI Key InChIKey=GESBEDAZDXKNGG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50560909   

TargetHistone deacetylase 6(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human HDAC6 expressed in HEK293/T17 cells using pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 80nMAssay Description:Inhibition of human HDAC1 expressed in HEK293/T17 cells pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 281nMAssay Description:Inhibition of human HDAC2 expressed in HEK293/T17 cells pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 443nMAssay Description:Inhibition of human HDAC3 expressed in HEK293/T17 cells pre-incubated for 10 mins before Ac-GAK(Ac)-AM substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 614nMAssay Description:Inhibition of human HDAC8 expressed in HEK293/T17 cells pre-incubated for 10 mins before Boc-Lys(TFA)-AM substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human HDAC7 expressed in HEK293/T17 cells pre-incubated for 10 mins before Boc-Lys(TFA)-AM substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of human HDAC5 expressed in HEK293/T17 cells pre-incubated for 10 mins before Boc-Lys(TFA)-AM substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human HDAC9 expressed in HEK293/T17 cells pre-incubated for 10 mins before Boc-Lys(TFA)-AM substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of human HDAC4 expressed in HEK293/T17 cells pre-incubated for 10 mins before Boc-Lys(TFA)-AM substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
The George Washington University

Curated by ChEMBL
LigandPNGBDBM50560909(CHEMBL4759584)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human HDAC11 expressed in HEK293/T17 cells pre-incubated for 10 mins before Boc-Lys(TFA)-AM substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed