BDBM50560986 CHEMBL4760200

SMILES COc1cccc(Nc2ccc(Cl)c3n(C)c(cc23)C(=O)NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)c1

InChI Key InChIKey=KLJDIOIKUPMBNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50560986   

TargetFructose-1,6-bisphosphatase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50560986(CHEMBL4760200)
Affinity DataIC50: 70nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) using FBP as substrate in presence of PGI and G6PDH by spectrophotometric me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed