BDBM50561537 CHEMBL4783529

SMILES FC1(F)CN(C1)C(=O)c1nc2cccnc2n1-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KQDYNRPFUNNOAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50561537   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50561537(CHEMBL4783529)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50561537(CHEMBL4783529)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50561537(CHEMBL4783529)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of sigma2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50561537(CHEMBL4783529)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5HT2C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed