BDBM50561594 CHEMBL4790505

SMILES CN1Cc2cc(ccc2NC1=O)N=[S@@](C)(=O)c1ccccc1

InChI Key InChIKey=JZDYWTRPAXOUIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561594   

TargetBromodomain-containing protein 4(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50561594(CHEMBL4790505)
Affinity DataIC50: 500nMAssay Description:Inhibition of BRD4 in human HEL cells harboring JAK2 V617F mutant assessed as decrease in metabolic activity measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50561594(CHEMBL4790505)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BRD4 in human MOLM-14 cells harboring FLT3-ITD mutant assessed as decrease in metabolic activity measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed