BDBM50562508 CHEMBL4789762

SMILES CC(C)CN(CC(C)C)c1ccc(cc1NCNc1nc(ns1)C(F)(F)F)[C@H](C)CC(O)=O

InChI Key InChIKey=XBWKGLPRWBFNKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562508   

TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562508(CHEMBL4789762)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as effect on KYN level incubated for 48 hrs by rapidfire-mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562508(CHEMBL4789762)
Affinity DataIC50: 39nMAssay Description:Inhibition of human 6His/FLAG-tagged/Avi/TEV-fused IDO1 expressed in Escherichia coli by absorbance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed