BDBM50562760 CHEMBL4750447

SMILES CCCCCCCCCn1ccc2cc(ccc12)-c1noc(n1)[C@@H]1CCCN1C(N)=N

InChI Key InChIKey=NGLWMNMJXLRMQJ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50562760   

TargetSphingosine kinase 2(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50562760(CHEMBL4750447)
Affinity DataEC50:  170nMAssay Description:Inhibition of recombinant human Sphk2 expressed in yeast strain KYA1 assessed as increase in yeast growth measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50562760(CHEMBL4750447)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of recombinant human Sphk2 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50562760(CHEMBL4750447)
Affinity DataKi: >10nMAssay Description:Inhibition of recombinant human Sphk1 expressed in baculovirus infected Sf9 insect cells using d-erythro-sphingosine as substrate measured after 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed