BDBM50562872 CHEMBL4787131

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1NCCNC(=O)CCNc1ccc([N+]([O-])=O)c2nonc12

InChI Key InChIKey=XJITUAXHAOUEQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562872   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562872(CHEMBL4787131)
Affinity DataIC50: 10nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562872(CHEMBL4787131)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 (DE3) using tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed